Drug Delivery Systems in Urology-
Getting "Smarter"
O. Farokhzad et al, Urology(2006) 68:463-469
In this review of drug delivery systems in the area of Urology, Farokhzad and colleagues detail the unique opportunity the genitourinary tract presents for site specific delivery of medical agents and discuss in detail many of the emerging technologies and approaches being investigated today. Due to the relative ease of access to the kidney, bladder, and prostate there are several minimally invasive options for localized delivery that could be carried out in the clinic setting. This offers the possibility of delivering the maximum therapeutic benefit while minimizing patient discomfort. The current intravesical and intraprostatic approaches are being supplemented by some novel new delivery vehicles due to advancements in materials science, biomaterial development and tissue engineering. Biodegradable shape-memory polymers, smart gels, nanoparticles and microscale drug delivery devices are all being investigated and tested as options for targeted delivery of compounds. The authors conclude that these advancements will help to shape the future of urological clinical practice. We at AbbeyMoor couldn't agree more. Hmm... A drug eluting stent for the prostate?
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